Image Representing Why do smokers have a higher risk of Alzheimer's?

Why do smokers have a higher risk of Alzheimer's?

The risk of Alzheimer's disease may rise with tobacco use. Recognize the numerous negative impacts of tobacco use.

by Nagpur Trends Team | Published on 2025-02-12 22:46:07

Alzheimer's disease is a neurological condition that causes memory loss and cognitive deterioration. The symptoms of this disorder are largely triggered by lifestyle factors, aging, and genetics. Nonetheless, it has been noted that smoking exacerbates Alzheimer's.

"Cigarettes contain toxic chemicals like nicotine, carbon monoxide, and formaldehyde that affect the brain," explained Dr. Aashka Ponda, Bhailal Amin, in an interview. Nicotine can lead to long-term brain damage and is extremely addictive.

Neurotransmitter activity is overstimulated. Long-term exposure throws off the acetylcholine balance, which is crucial for memory and learning. However, another dangerous ingredient in cigarettes that lowers the amount of oxygen reaching the brain is carbon monoxide. Frequent exposure to carbon monoxide and nicotine can raise the risk of Alzheimer's disease."

The body produces free radicals that harm cells when it metabolizes tobacco smoke. Due to its low antioxidant defenses and high oxygen requirements, the human brain is susceptible to oxidative stress.

Oxidative stress is a major factor in the buildup of beta-amyloid plaques, which are toxic protein clusters that disrupt neuronal transmission and cause brain cell death in Alzheimer's patients, the neuro-physician continued.